The river : a journey to the source of HIV and AIDS / by Edward Hooper.
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- ISBN: 0316372617
- ISBN: 9780316372619
- ISBN: 0316371378
- ISBN: 9780316371377
- Physical Description: xxxiii, 1070 pages : illustrations, maps ; 24 cm
- Edition: 1st ed.
- Publisher: Boston, MA : Little, Brown and Co., ©1999.
Contents / Notes
Includes bibliographical references and index.
I. The river in cross section: frozen moments of flow : Frozen in time: 1959 ; Frozen in space: a rural epicenter in Africa -- II. From trickle to flood: "A mysterious microbe": early evidence of AIDS in North America ; High days and holidays: the Haitian interchange ; Early traces in Europe ; HIV and AIDS in Central Africa ; False positives, and the specter of contamination ; The Manchester sailor ; AIDS in the pre-AIDS era? -- Theories of origin, propounded and refuted ; Gerry Myers and the monkey puzzle tree -- III. A new hypothesis of source : AIDS and polio vaccines ; The race to conquer polio: early research and inactivated polio vaccines ; The race to conquer polio: oral polio vaccines ; Dr. Dick and Dr. Dane ; "What happens when science goes bad" ; Louis Pascal ; The counterattack begins -- IV. European feeders : An untimely passing ; The Congo trials ; Primate immunodeficiency viruses ; Pierre Lépine and the Pasteur Institute ; The Norwegian sailor ; Switzerland and Sweden ; An introduction to HIV-2 ; Paul Osterrieth and Fritz Deinhardt ; The quieting of Louis Pascal -- V. The passage through the pools : A man of many ideas ; Hilary Koprowski, opening moves ; The West coast trials ; The East coast trials, and the question of informed consent ; At the CDC ; Tom Norton ; Hilary Koprowski, end game ; Other views, other voices, from Lederle to the Wistar ; David Ho -- VI. Whirlpools and sinkholes : Bill Hamilton ; The two sailors ; From the archives ; Ghislain Courtois ; Stanley Plotkin ; Le Laboratoire Médical de Stanleyville ; The chimpanzees ; The Belgian vaccine ; The threats begin ; Alexandre Jezierski -- VII. Charting the course : The HIV-2 enigma ; Infection by mouth ; Preston Marx and an alternative hypothesis ; Natural or iatrogenic transfer? ; What happened at Letchworth and Clinton ; What happened at Lindi ; Where CHAT was fed ; Correlations with early HIV and AIDS ; Starburst and dispersal ; Dead ends and hidden bends -- VIII. How a river is born : The rechanneling of history ; When the levee breaks -- Appendices : A. Arguments for and against the OPV/AIDS hypothesis ; B: Experiments and investigations that could be conducted to shed further light on the OPV/AIDS hypothesis.
"Based on over a decade of research, involving more than 600 interviews and analysis of more than 4,000 scientific texts, The River examines the myriad theories about the origin of the AIDS epidemic - and reaches a stunning and startling conclusion." "Since the early nineties, serious HIV researchers have been aware that the most common variant of HIV - human immunodeficiency virus - is the direct descendant of an SIV - simian immunodeficiency virus - carried by African chimpanzees." "Many doctors and scientists think the transfer was "natural," the result of human/chimp encounters - either from the keeping of chimps as pets, or from hunting and skinning chimps for food." "Others, including Edward Hooper, believe it more likely that the transfer was the result of American and European medical interventions in Africa during the 1950s - and specifically the administration of more than a million doses of an experimental oral polio vaccine, some batches of which may have been manufactured from chimp kidneys. The maps of vaccinations and early AIDS cases are extraordinarily similar."--Jacket.